Department Chair, Professor
juan.gutierrez3@utsa.eduFLN 4.01.10
Mathematical Biology
Multiscale modeling; Bioinformatics; Machine Learning
Curriculum Vitae (20-page detailed CV).
Resume (2-page executive summary).
https://biomathematicus.me
Before mathematics, I had a career as a fiction writer. The following list of literary publications, peer-reviewed articles about electronic literature, and articles/theses/dissertations about my literary work is also available at https://mathresearch.utsa.edu/wp/?p=1360
Regarding this area, I am particularly interested in: (i) artificial intelligence applied to storytelling, (ii) digital narratology (or digital neo-structuralism), (iii) narrative bots, and (iv) natural language processing. I believe that storytelling is an essential state of human minds, and that it can be mediated by digital technologies.
| 2006 | Novel. El primer Vuelo de los
Hermanos Wright (The first Flight of the Wright Brothers). Written with the support of Award #COLCULTURA-SECAB 014/1996 by the Instituto Colombiano de Cultura - Colcultura, now the Ministry of Culture of Colombia. 1996-1998 |
| 2005 | |
| 2000 | Story. Las Fricciones de San
Sebastián. (The Frictions of St. Sebastian).
Revista Avianca. Magazine of Avianca Airlines. Number
254. Bogota. Colombia. Mar, 2000. Pag. 66-69. Bogota,
Colombia. |
| 2000 | Story. La Sagrada Geometría
(The Sacred Geometry.) In Antología Colombiana
de Ciencia Ficción (Companion of Colombian
Science Fiction). Pag. 93-96. Rene Rebetez (ed.) Espasa,
2000. Bogota, Colombia.
ISBN: 958-614-804-1 |
| 1998 | Story. Las Exquisitas Disquisiciones
de Fray Leonardo Baz. (The exquisite reasoning of
Father Leonardo Baz.) Gaceta. Magazine of the
Ministry of Culture of Colombia. Pag. 150-145. Num.
44-45. Bogota, Colombia. 1999.
ISSN: 0121-7194 |
| 1996 | Short Story Book. Siete Curiosas Formas
de Morir. (Seven Curious Ways to Die). Unidad
de Publicaciones. Facultad de Ingeniería. Universidad
Nacional de Colombia. 1996. (Press of the School of Engineeering of the National University of Colombia.) |
| 1996 | Story. González, Archivos
y Documentos. (Gonzalez, Files and Documents.) In Sunday Readings of El Tiempo (Sunday Readings from
The Times), newspaper. ISSN: 0121-9790.
Also in Carta Universitaria, Magazine of the National
University, December 1996. Bogota, Colombia.
ISSN: 0122-2929 |
| 1995 |
Story. La Sagrada Geometría
(The Sacred Geometry.) In Crea, Una Expedición
por la Cultura Colombiana (CREA: An Expedition through
the Colombian Culture). Ministry of Culture of Colombia
(formerly Colcultura). Page 17-22. |
| 1995 | Story . Atyseikuiwandiú,
o los Avatares de la Cruel Sangre (Atyseikuiwandiú,
or the Fortune of the Cruel Blood). In Lecturas
Dominicales de El Tiempo (Sunday Readings from The
Times), newspaper. 01/15/1995. Bogota, Colombia.
Also in Ko'eyú, Journal of Cultural and Politic
Analysis. Number 64, April-June 1994. Caracas, Venezuela. |
| 2010 | CHAPTER. L Borràs, JB Gutierrez. The Global Poetic System (GPS): A System of Poetic
Positioning. Chapter 15, pp. 345-364. Beyond the Screen: Transformations of Literary Structures,
Interfaces and Genre. Peter Gendolla, Jörgen
Schäfer, Eds. Transcript Verlag, 2010. Bielefeld,
Germany. |
| 2009 | JOURNAL. JB Gutierrez, Mark C. Marino,
Pablo Gervás, Laura Borràs Castanyer Electronic
Literature as an Information System. In Hyperrhiz:
New Media Cultures. Issue 6, Summer 2009. |
| 2008 | PROCEEDINGS. JB Gutierrez and MC Marino. Literatronica.
Adaptive Digital Narrative. In Creating '08:
Proceedings of the hypertext 2008 workshop on Creating
out of the machine: hypertext, hypermedia, and web
artists explore the craft, pages 5-8, New
York, NY, USA. |
| 2007 | CHAPTER. JB Gutierrez. The Limits
of Digital Narrative: A Functional Analysis.
Chapter 5, pp. 85-103. Literatures
in the Digital Era: Theory and Praxis. Amelia
Sanz, Dolores Romero, Eds. Cambridge Scholars Press,
2007. UK/Spain. |
| 2006 |
PROCEEDINGS. JB Gutierrez. Literatronic:
The use of Hamiltonian cycles to produce adaptivity
in literary hypertext. In The
Bridges Conference 2006: Mathematical Connections
in Art, Music, and Science, pages 215-224, London,
UK, August 2006. |
| 2004 | JOURNAL. JB Gutierrez. Hipertexto
Literario: Replantemianto de las premisas. (Literary Hypertext:
Rethinking the premises.) Hojas
Universitarias. Journal of the School of Humanities of the Universidad
Central, (56):128-132. Bogota, Colombia, October 2004. |
| 2000 | JOURNAL. JB Gutierrez. Hipertexto
en Contexto III. (Hypertext in context III.) In Signo
y Pensamiento. Journal of the School of Communication
of the Pontificia Universidad Javeriana, XIX(36):111-118.
Bogota, Colombia, 2000. |
| 1999 | JOURNAL. JB Gutierrez. Hipertexto
en Contexto (Hypertext in Context.) In Revista
de Literatura Hispanoamericana. (Journal of Latin-American
Literature). Journal of the School of Literature of
the Zulia University (38):83-90, Jan-Jun 1999.
Maracaibo, Venezuela, 1999.
ISSN: 0252-9017 |
| 2021 | Colombia. Dissertation. Julian Alberto Cubillos Ocampo Alfabetización mediática en r evolución digital y literatura electrónica. (Doctoral dissertation, UNIVERSIDAD DE LOS ANDES, COLOMBIA. |
| 2017 | USA. Article. Melissa Fitch Latin American Literature and NewTechnology. In Critical Insights - Contemporary Latin American Fiction, Ignacio López-Calvo Ed. Salem Press, Gey House Publishing. |
| 2015 | USA. Dissertation. Julio Alejandro Pérez Digital Storytelling in Spanish: Narrative Techniques and Approaches . (Doctoral dissertation, UNIVERSITY OF CALIFORNIA, SANTA BARBARA). |
| 2015 | Germany. Dissertation. Klöpper-Mauermann,
S. Die
spanischsprachige Hyperfiction und ihr Leser: narratologische Auslotungen
einer schwierigen Beziehung. (Doctoral dissertation, UNIVERSITY
OF HAMBURG). |
| 2015 | Iceland. MA Thesis. Nevena Novakovic El uso de la literatura digital en el aula de
ELE . (MA Thesis, UNIVERSITY OF ICELAND). |
| 2014 | Spain. Article. Linares, J. M. G. (2014). Literatrónica:
un análisis hipertextual de Condiciones extremas, de Juan
B. Gutiérrez. Álabe: Revista de Investigación
sobre Lectura y Escritura, (9)6, 2014. |
| 2013 | USA. Dissertation. Gainza, C. (2013). Escrituras
Electrónicas en América Latina. Producción
Literaria en el Capitalismo Informacional (Doctoral dissertation,
UNIVERSITY OF PITTSBURGH). |
| 2012 | Colombia. MA Thesis. Primeros
apuntes para una historia de la literatura digital en Colombia desde
1990 hasta el 2012 (MA Thesis, UNIVERSIDAD DE LOS ANDES). |
| 2010 | USA. MA Thesis. Fordyce, T. (2010). Linked
variations: authoring-system specific link construction and the
analysis of hypertext literature (MA Thesis, GEORGETOWN UNIVERSITY). |
| 2010 | Agentina. Article. Cobo, R. M. D. (2013). Modelos
para armar: hacia la digitalización de la narración
literaria. CELEHIS: Revista del Centro de Letras Hispanoamericanas,
19(21), 47-72, 2008. |
| 2009 | USA. Dissertation. Cleger, O. (2009). El
arte de narrar en la era de las blogoficciones: Una aproximacion
interdisciplinaria a la literatura en los blogs (Doctoral dissertation,
THE UNIVERSITY OF ARIZONA). |
| 2008 | USA. Dissertation. Acuna-Zumbado, E. (2008). Hacia la
construccion del sujeto y sus procesos de lectura en la hipertextualidad
latinoamericana (Doctoral dissertation, UNIVERSITY OF KANSAS). |
| 2007 | Colombia. Article. Henry, P. S. (2013). Metamorfosis
literaria en la era digital: El primer vuelo de los hermanos Wright.
Cuadernos de Literatura, 12(23):142-452, 2007. |
| 2007 | UK/USA/Spain. Chapter in book. Perla
Sasson-Henry. From Hypertexts To Blogs: "El
Primer Vuelo De Los Hermanos Wright" And "Más
Respeto Que Soy Tu Madre." Chapter 20, pp.
319-328. Literatures
in the Digital Era: Theory and Praxis. Amelia
Sanz, Dolores Romero Eds. Cambridge Scholars Press,
2007. UK. |
| 2002 | Germany. Article. Jochen Mecke. Ästhetische
Differenz in Print- und Hypertext (fiktion) (Aesthetic
difference in print and Hypertext fiction). PhiN-Beiheft
2/2004: 141. Philologie im Netz. (Philology in Net).
Journal of philology of the University of Berlin.
Germany.
ISSN: 1433-7177 |
| 2001 | USA. Chapter in book. Susana Pajares
Tosca. Condiciones Extremas. Digital Science Fiction
from Colombia. Latin American Literature and Mass Media.
Garland. Hispanic Issues Series. New York, 2001.
ISBN: 081-533-894-5. |
I am passionate about social justice and mathematics in general, and specifically about mathematical biology in my own research. I envision research in quantitative biology as a constant exchange of ideas between experts in quantitative fields (i.e. computer science, engineering, mathematics, physics, statistics) and experts in biological sciences. This conversation enriches biology with the insight provided by quantitative methods, and it enriches quantitative fields with the demands of complex problems originated in biology. Joel Cohen put it succinctly and brilliantly: “mathematics is biology’s next microscope, only better; biology is mathematics’ next physics, only better“.
I have worked on recently on the following areas:
Machine learning: We use machine learning on a regular basis, but we are also developing new algorithms that improve the performance of artificial neural networks as compared to the state of the art. Also, I have been involved in applications of machine learning to analysis of cardiac signals, text summarization, and student success at the university level.
Data harmonization: We are able to represent heterogeneous and complex data sets of arbitrary size with a reduced set of data primitives (well-defined mathematical objects that are the building blocks to represent reality). Our analysis pipelines only consume data primitives, and only produce data primitives. The ultimate goal is to design and implement an agent capable of automated knowledge discovery.
Adaptive learning: The training of interdisciplinary scientists poses tremendous challenges. This is particularly true when teams are composed of people with heterogeneous backgrounds. We have developed technology that minimizes the cognitive overhead to train individuals, and to integrate teams into a research project.
Multi-scale analysis of infectious disease: We study mechanisms that connect multiple scales, from milliseconds through evolutionary time, and from quantum interactions through continental dynamics of infection. This endeavor requires advances in multiple areas, as described below. We have been able to produce advances in every single aspect, and we are capable of integration of all these dimensions.
Epidemiology of asymptomatic carriers: We study the effect of asymptomatic hosts in the dynamics of malaria transmission. The results can be extrapolated to other diseases.
Dispersal of vectors: We study methods to model the dispersal of mosquitoes in a heterogeneous landscape dominated by species distribution, climate, and vegetation cover.
Physiology: We are able to identify when a host is infected before the onset of symptoms occurs. We accomplish this via high-frequency measures of accelerometers, blood pressure, ECG, and temperature.
Cellular models of immune interaction: We are using flow-cytometry data and cytokine information during a malaria infection to model cellular-level interactions between the adaptive and innate immune system, and healthy and infected red blood cells.
Multi-omic integration: We are able to analyze transcriptomic data, and integrate it with proteomics, metabolomics, immunomics, and other -omic technologies. Using this type of integration we have been able to determine factors that confer resilience against an infection.
Computational Drug Design: Given a gene regulatory network (that we can reconstruct from a time series of transcriptomic data), we can identify the most sensitive elements of the network, and target them with molecular docking studies against databases of drug-like molecules.
