Date: March 24, 2018
Location:Downtown UTSA Campus, Durango Building
Time: 1:30 PM - 2:30 PM
Dr. Yufei Huang
UTSA Electrical and Computer Engineering
Transcriptome methylation is an exciting, emerging area that studies methylation in the transcriptome. In contrast to well-established DNA methylation, transcriptome methylation is largely an uncharted territory. In this talk, I will report our recent effort in developing machine learning tools to predict transcriptome wide N6-methyl-adenosine (m6A) methylation sites, context specific differential m6A methylation sites, and driver m6A sites from high throughput sequencing data. I will also report how we use these tools to elucidate the dynamics of transcriptome wide m6A methylation in the course of Kaposi's sarcoma-associated herpesvirus (KSHV) infection of mammalian cells. I will conclude the talk with discussion on the outlook and future directions of this area.
Friday, November 10th
4:00 - 5:00 PM